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The results showed that gelatin-coated TCP scaffold with rhBMP2 delivery system not only could act as a mechanically and biologically compatible framework, but also act as an osteoinductive graft by sustained delivering of rhBMP2 in a therapeutic window for differentiation of hBFPSCs towards the osteoblast lineage.
In comparison with saline and EPO treatment, sustained delivering of EPO by PLGA microspheres demonstrated the most significant improvement in recovery of injured circular bundles.
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The Ozurdex® (Ozurdex®; Allergan, Inc, Irvine, CA, USA) dexamethasone drug delivery system (DDS) is a biodegradable intravitreal implant that delivers sustained release of 700 μg of preservative-free dexamethasone to the retina and vitreous.
Therapeutic efficacy, however, has been limited by diffusion or inactivation of these growth factors from the desired site and by the inability to deliver sustained concentrations of growth factors.
The Liverpool Care Pathway is an integrated care pathway used at the bedside to deliver sustained quality of care for the dying in the last hours and days of lifec.
Most fully closed-circuit rebreathers can deliver sustained high concentrations of oxygen-rich breathing gas and could be used as a means of supplying oxygen if dedicated equipment is not available.
Several studies have shown promising results in the ability of microspheres to deliver sustained and constant quantities of bioactives as they can effectively be combined with more than one delivery system to control the release kinetics [ 50, 102, 103].
delivered of a son.
Here we test the ability of the AAV1-F9 vector to deliver sustained expression and correction of factor IX (FIX) deficiency in genetically engineered hemophilic mice.
We are all used to sneering at communism because of its manifest failure to deliver the sustained rates of growth managed by market economies.
One possible cause for failure of GAG inhibition in vivo is the inability to deliver a sustained concentration of GAG at the mucosal surface.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com