The clinical appearance is highly variable, involving sustained cough, erythema nodosum, periarticular inflammation, fever and occurring fatigue.
Furthermore, those who contract pertussis later in life may go undiagnosed, but their sustained cough spreads the infection among family, friends, associates and health care workers [ 2, 6, 7, 13, 15- 17].
Indeed, the smallness of the infraction somehow makes it worse: to get so close to perfect silence, only to have it punctured by the crinkle of a wrapper, rankles more than someone having a sustained coughing fit.
Extubating conditions assessed during removal of the tracheal tube were defined as follows: excellent = no coughing and no movement of the limbs, good = slight coughing or slight movement of the limbs or both; poor = sustained coughing and/or vigorous movement of the limbs during extubation.
A national strategy to improve cancer outcome in Denmark was introduced in 2008, including, among others, a fast-track diagnostic pathway for suspected cancer cases; this implied that patients with specific symptoms (e.g. sustained coughing) were to be seen at the hospital within three days after referral [ 3, 4].
Physicians were asked if the patient had experienced one of the following since the previous visit: progressive dyspnea, increased cough, sustained decrease from baseline in absolute FVC and DLCO, progression of fibrosis from baseline on HRCT, AEx, respiratory failure, or new need for supplemental oxygen or increase in oxygen requirements.
In truth we have no cogent explanation why, as in other observations [ 1, 8] there is sustained damping down of cough reflex sensitivity to citric acid with the Mefar technique and why this is not seen with the KoKo DigiDoser.
Despite the emphasis on prevention and surveillance, concerns about mold-related symptoms have surfaced ("Katrina Cough") and need sustained attention to assure that unexpected problems are identified and revised prevention messages are disseminated as quickly as possible.
In the future, longer-acting formulations of cough-suppressing agents using extended-release technology to deliver sustained relief, or existing agents used in novel combinations may play an important role in developing more optimal treatments for acute cough.
Information at the meeting affirmed that SARS is spread principally by droplets dispersed in coughs and sneezes among people with close and sustained contact with an infected individual.
Yet there is little evidence that proton pump inhibitors and nasal steroids have any real sustained benefit in the treatment of acid- and postnasal drip-associated cough.
