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First, we demonstrated that PRP sustained cell viability and meanwhile promoted cell migration from the interior of alginate microspheres to the surface.
Samples B and D sustained cell viability during one week in a similar extent as the control hydrogel did, as no significant differences were registered between them.
As the macrophages are not greatly affected by bisphosphonate treatments when cultured on bone [ 62], this could explain the sustained cell viability despite a decrease in the number of osteoclasts.
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Tzb-resistance selection continued until the SKBR3 cell population could sustain cell viability and proliferate when challenged with 200 µg/ml Tzb.
Mutant subunits that do not sustain cell viability have been studied after ectopic expression in addition to the endogenous copy (Arumugam et al, 2003; Weitzer et al, 2003).
As a trend, higher HES molecular weight seems to sustain cell viability (with notable exception for protocol 5) but only in FCS not in DMEM.
In order to sustain cell viability and recover from injury, cellular responses to stress include steps that attempt to preserve mitochondrial integrity.
In addition, there were very low levels of apoptotic and necrotic cells), which indicated that these 3D dynamic culture conditions are a suitable method to sustain cell viability also for neuronal-like cells.
These results suggest that SCC-9 cells may utilize the autophagic pathway as a survival mechanism to evade the perturbations of cellular biosynthetic processes by the antimetabolite MTX and sustain cell viability upon metabolic stress.
It has been suggested that increased trehalose content in S. cerevisiae sustains cell viability during the initial stages of fermentation and thus results in higher carbohydrate utilization rates [ 41].
The finding that several dozen proteins species are required to sustain cell viability in the presence of unsaturated FA suggests an enormously complex network of processes and interactions to maintain membrane homeostasis and function (Lockshon et al. 2007).
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