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The sustainable expression of such constructs obviates some of the problems that may be encountered with long GPCR mRNA turnover rates.
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Although the expression "sustainable construction" is being used more and more, it is necessary to distinguish between the sustainability of the construction activity and the sustainability of works constructed.
The corporate image has been at the centre of this evolution, with architects striving to design for an iconic sustainable facade expression.
Consequently it segregates into daughter cells, which enables sustainable transgene expression.
For example, retrovirus murine leukemia virus (MLV) has been used as a viral vector to establish sustainable transgene expression in humans [ 7, 8].
Virus-mediated transfection is highly efficient and it is easy to achieve sustainable transgene expression in vivo owing to the viral nature of integration into the host genome.
To address this, the γ-retroviral vectors are being increasingly replaced by self-inactivating (SIN) retroviral vectors, which in pre-clinical studies have shown similar efficacy in terms of sustainable transgene expression, but reduced tendency for harmful mutagenesis (Seymour and Thrasher, 2012).
The author focuses on the environmental aspect of the expression "sustainable".
The five axes of sustainable development are expressions of: prosperity, equality, and governance; quality of life; ecosystem integrity; environmentally efficient happiness; and environmental management.
In these studies, using the COS-7 culture system, long-term decreases in COMP expression were sustainable for up to two weeks in the presence of recombinant COMP (Fig. 4).
Higher and sustainable responses including elevated expression levels of IP-10 and IL-12b were observed in case of T. gondii II and III strains, but not for type I strains.
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