Sentence examples for sustain their expression from inspiring English sources

This triad also forms an autoregulatory circuit, in which, by binding to their own promoters, as well as to the promoters of Oct4, Sox2 and Nanog they collaborate to sustain their expression.

We also analysed the mRNA expression levels of these EZH2 target genes and found that they were significantly increased for PPARγ and PIP5K1C but not for the osteogenic-specific RUNX2 during neuron differentiation, which peaked on Day 1 and then gradually decreased to a level higher than undifferentiated hMSCs on Day 5, presumably to sustain their expression (Fig 4E).

Interestingly, when analyzing the expression of the LBR in the interfollicular epidermis, we identified suprabasal cells, in the progeroid animals, that have sustained their expression.

Embryonic stem cell (ESC) pluripotency is maintained by core transcriptional circuits whereby critical factors sustain their own expression while preventing the expression of genes required for differentiation.

Quantifying LBR-positive suprabasal cells showed that 14.06% (SEM 5.7%) of the suprabasal cells of the interfollicular epidermis in the progeroid animals at PD9 had sustained their LBR expression (N = 3) (Fig. 6M).

Whereas pRb-expressing osteoblasts sustained their basal N-cadherin expression at 14 dbc, N-cadherin expression was decreased in pRb-deficient osteoblasts at this time point (Fig. 3C, top panel).

Next, we assessed their localization by immunocytochemistry, which confirmed their sustained expression levels as well as their localization in growth cones of serum-deprived PC12-ND6 cells.

These data lend further support to the hypothesis that the diversification of Aux/IAA family members in flowering plants has been sustained by changes in their expression patterns.

We speculated that E2 might sustain the expression of CCR7 on Th17 cells and thereby hamper their egress from LNs.

During neurogenesis, genes that determine the transition from the proneural state to neuronal or glial lineages are oscillating before their expression is sustained.

In JMJD2B siRNA-treated HCT116 cells, p-Chk2 was detected as early as 6 h and their expression was sustained for 24 h in hypoxia.