KEGG pathways analysis sustains the implication of the tumor microenvironment in the identified tumor subgroups (see Additional file 1: Table S1 for the list of deregulated KEGG pathways).
It may not be 1991 or 1998 all over again for Russia, but today's financial misfortune means that several of Putin's tools of economic control and influence will now be less sharp - and over time, if sustained, the political implications of this may come to matter just as much.
It appears clear that utilization increased where free care was effectively available, but implementation difficulties, most notably under-funding of the programme, implied that effective free care (at least as judged by users) was not sustained, with the implication that higher rates of utilization also could not be sustained.
If our legal system cannot sustain the prosecution of a murderer for his crimes, the implications for our society and its laws are catastrophic.
However, forest clearing is spatially pervasive and fragmented in the landscapes studied to date, with implications for sustaining the region's biodiversity.
Without rejecting any kind of this-worldly sovereign statehood, this form of other-worldly statehood may have instructive implications for sustaining the Open Science knowledge space as an inclusive, diverse and peaceable space in, of and above the existing global system of states and transnational capitals.
In addition to the efficacy of IPTi, the costs associated with introducing and successfully delivering the intervention as part of an integrated health system have been studied in detail [7], as have the policy implications of introducing and sustaining the delivery of IPTi [2], [8], [9] and the perceptions of the communities who have received IPTi[10], [11].
The ability of a living organism to endure environmental challenges depends on the portion of genetic variation with adaptive implications [ 2] that sustains the formation of ecotypes through ecological evolution [ 3].
Achieving an integrated view of the signaling pathways sustaining the neurotoxicity of prions may have broad implications for designing therapeutic strategies to alleviate amyloid-associated neurodegeneration.
The judge sustained the objection.
