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Furthermore, MBG nanospheres can sustain release of doxorubicin (DOX) with a higher encapsulation efficiency (63.6%) and show distinct degradation in PBS by releasing Si and Ca ions.
Moreover the preparation process has to be compatible with protein encapsulation and the obtained matrix should be able to sustain release a model protein.
However, clinical use of statins (e.g., fluvastatin) is limited by the lack of a suitable delivery system to localize and sustain release.
Overall, the developed formulation was stable with sustain release of acyclovir over 10-12 h periods; hence can be a viable alternative to conventional dosage forms.
Here we investigate several existing strategies to sustain release of hydrophilic small molecule drugs that are highly-loaded in electrospun fibers.
Effect of temperature/pH dependent bi-phasic (burst initial followed by sustain) release of model chemotherapeutic molecule Doxorubicin on MCF7 (breast adenocarcinoma cells from human) is investigated comprehensively including MTS assay, calcein AM/ethidium bromide assay and actin filament arrangements.
Similar(37)
The sustained release of TTO from the hydrogel was studied.
A 6-h sustained release was observed in vitro.
Various medicated membranes exhibit the sustained release profiles.
Estradiol valerate provides for sustained release of estradiol.
They all allowed high loading and sustained release of acyclovir.
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