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Although these mechanisms can sustain cardiac function for a short time, chronic activation of sympathetic activity has adverse biological effects.
Mitochondrial metabolism appears critical to sustain cardiac function to counteract aging.
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Recent studies have indicated that circulating acylcarnitines can serve as an important fuel in sustained exercise (Seiler et al, 2014), and their increased release by liver and heart may be a mechanism that allows sustained cardiac function under conditions of substrate pool depletion.
Extracorporeal membrane oxygenation (ECMO) is a form of prolonged cardiopulmonary bypass used to temporarily sustain cardiac and/or respiratory function in critically ill patients.
Giordano, F.J. et al. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function.
On using chemical energy to support cardiac function.
Does Parkin-mediated mitophagy help to sustain cardiac mitochondrial fitness?
In the heart, AMPK activity increases during ischaemia and functions to sustain ATP, cardiac function and myocardial viability.
Therefore, we hypothesize that at 12 weeks of age cardiac hypertrophy is subsiding because the heart is no longer able to sustain adequate cardiac function.
Those living with RFA suffer severely impaired health-related quality of life (HRQL) including recurrent and sustained cardiac pain, psychological distress, impaired role functioning, activity restriction, and inability to self-manage [ 10, 11].
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia.
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