Sentence examples for sustain a defect from inspiring English sources

Furthermore, we hypothesize that the cancerous mammary epithelial cells sustain a defect in the ligand-dependent downregulation of ER-α, and that this defect in regulation of ER-α causes uncontrolled growth of the transformed cells in a hormonal environment with stimulatory pressure on the ER-α system, but they remain latent in a hormonal environment lacking this ER-α stimulation.

Ministers believe local authorities are in some cases deliberately preventing good schools from raising their "planned admissions numbers" because it becomes harder to sustain a weaker school if pupils defect.

Most other countries recognize only mental disease or defect of sufficient degree to sustain a defense of insanity.

My company can't sustain a disaster".

Euphoria cannot sustain a business, however.

They cannot sustain a long protracted war".

And third, the host must have a defect in immune regulation that allows induction of sustained immune responses against these antigens.

In conclusion, we identified an epigenetic signature of DS that sustains a link between developmental defects and disease phenotype, including segmental premature aging.

We now discuss a possible mechanism that can sustain the defect in RAD51 recruitment to DSBs in SETD2-depleted cells despite the lack of apparent alterations on RPA phosphorylation and foci formation.

After an initial opening and extension of the Teflon-induced embedded defect, the specimens sustained a high number of cycles.

While a sustained transport defect puts the neuron at risk of death, our data demonstrate that MAD is an early event that occurs prior to signs of neuronal cell death.