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The Stand Alone Test is a quantitative suspension test.
HE was assessed using neurocomportemental testing (6 minutes tail suspension test assessing the time of immobility).
In addition, compound 5i exhibited greater efficacy than fluoxetine in the tail suspension test.
Tail suspension test is another animal despair study adopted (Cryan et al. 2005) to access the antidepressant activity.
It has been argued that tail suspension test is less stressful than force swimming test and has greater pharmacological sensitivity.
exhibited depressant-like effects in forced swim and tail suspension test (in mice), without influencing the locomotor status.
For this study, the tail suspension test (TST), forced swim test (FST) and yohimbine lethality test were performed.
Open-field test(OFT), tail suspension test(TST) and forced swimming test(FST) were used to evaluate the behavioral activity.
Additionally, these active compounds also exhibited significant efficacy in tail suspension test (TST) (another model to screen antidepressant compounds).
Additionally, the experiment was extended to observe the tail suspension test allow as a fast and reliable screening of the psychotropic properties of drugs.
Other measures such as sweet water preference, inactivity time with forced swim test, and tail suspension test were not different at baseline between the KO and WT.
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