Sentence examples for susceptible to complement from inspiring English sources

We have seen previously that the majority of epimastigotes of T. cruzi strains are susceptible to complement killing in normal human serum at nearly physiological conditions (50% of serum at 37°C) after incubations ranging from 5 to 30 minutes (not shown).

This is consistent with the work done by R. Looney showing that the Vi capsule blocks C3 deposition on the surface of S. Typhi, and strains lacking Vi, such as the RASTyV strains used in this study, are susceptible to complement killing via the alternative (non-antibody) pathway [88].

After showing that different T. cruzi strains vary in their ability to resist the complement system, and that some strains are susceptible to complement killing, we decide to investigate how efficiently the complement system can control metacyclic trypomastigotes invasion of eukaryotic cells in an in vitro assay that simulates physiological conditions.

However, more or less, all enveloped viruses are susceptible to complement mediated lysis.

ILY directly competes for the membrane attack complex binding site on CD59, rendering cells susceptible to complement lysis.

The model also demonstrated that RPE cells with a defective version of Factor-H, a complement-system regulator protein, are more susceptible to complement attack when exposed to a potentially toxic metabolite from photoreceptor outer segments (Radu et al., 2014).

"Unencapsulated" mutants of F. tularensis LVS have been described that are highly susceptible to complement-mediated killing [21], [23].

Strikingly, we detected that metacyclic trypomastigotes of some T. cruzi strains were highly susceptible to complement-mediated killing in non-immune serum, while other strains were resistant.

Other trypanosomatids, such as Leishmania sp. and Chritidia sp., have been shown to be highly susceptible to complement-mediated killing in human serum [36], [46], [47], indicating that the complement system can act as a physiological barrier for trypanosome infection.

All blood cells are susceptible to complement-mediated attack, although red blood cells are the most susceptible to lysis (Parker, 1991; Pu & Brodsky, 2011).

A further possibility is that there are intrinsic properties of the male kidney that render it more susceptible to complement-mediated injury.