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Until specific susceptibility genes are discovered, the identification of environmental risk factors that primarily affect susceptible subgroups may require us to refine ASD subgroup classifications using specific phenotypic patterns or the clustering of ASDs in families.
In particular, studies of genetically susceptible subgroups may enable the detection of low levels of risk due to certain common exposures that have eluded traditional epidemiologic methods.
c) Studies are needed to identify susceptible subgroups.
There is also the possibility of susceptible subgroups and other disease end-points.
The susceptible subgroups were chosen based on a literature search and defined prior to analyses.
We evaluated the findings on potentially susceptible subgroups across studies of PM2.5.
We also summarize the findings on potentially susceptible subgroups across studies.
Confounding and interaction should be considered to ensure robust estimates and define susceptible subgroups.
Hence, the association between HRV and PM exposure is not only seen in susceptible subgroups.
A more recent development is the explicit inclusion of sensitive or susceptible subgroups.
Environmental factors are an attractive target for disease prevention, especially when susceptible subgroups within the population can be identified.
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