This kills off only the susceptible forms of the microbes, allowing the more resistant versions to remain and dominate.
By understanding the concept of relative fitness for resistant versus susceptible forms, savvy physicians have been able to devise drug treatment regimens that render infections more amenable to treatment with available drugs (Palumbi 2001).
Increases in the absolute number of some other viral variants, however, paralleled rises in viral load, suggesting that, prior to escape, specific T-lymphocyte responses directed to susceptible forms of these epitopes had effectively suppressed viral replication.
A fitness cost to pesticide resistance results in a fitness trade-off, where resistant forms perform better than susceptible forms when pesticides are present, but perform worse when pesticides are absent (Fig. 1, Gassmann et al. 2009; Cao et al. 2014).
Multiple co-circulating minor CXCR4-using viruses were found to exist in chronic infection, and the virus simultaneously explored many escape routes as the drug-susceptible form was selected against.
This is susceptible to form various carbonates with different stability, thus affecting and potentially decrease the material degradation rate.
Indeed, tumours displaying local lymph node metastasis (stage III) or distant metastasis (stage IV) are more susceptible to form colospheres than are stage I and II tumours.
Through different analyses of our results, we could identify chimeras which maintain the ORFs of Csnk2b and Ly6g5b susceptible to form bi-functional chimeric proteins in Homo sapiens, Macaca mulata, and Sus scrofa.
Interestingly, we have also found that some patients with gallstone gathered in some families and the individuals with a familial background were more susceptible to form cholesterol stones than those without a familial background.
The researchers trialled the test on genetically modified mice, which are highly susceptible to forming tumours.
