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When one speaks of "probability" of response in this context, one is referring to the chance that a randomly chosen individual of unknown susceptibility is found to be susceptible enough to be a responder at the dose in question.
But now scientists have shown that a genetically engineered rat is susceptible enough to HIV infection that it may be able to help evaluate some AIDS drugs.
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Even for a highly regarded ambassador with a dash of Lawrence of Arabia's empathy and mistaken sense of invulnerability, Stevens was obviously too lightly guarded in a region roiling with threats and hatred; he was in a susceptible complex without enough armed security and basic emergency equipment.
As hygiene improved, the certainty of young people of successive generations being exposed to the virus was gradually reduced, and in that new situation it was not long before enough susceptible children and adults had accumulated to allow epidemics to break out.
The virus may have taken hold when the dolphin population reached a tipping point, with enough susceptible individuals to sustain its spread, says veterinary epidemiologist Stephanie Venn-Watsof of the National Marine Mammal Foundation in San Diego, California.
Once enough susceptible persons have been identified, the outbreak control agency may apply the RPORITA prediction by simply vaccinated the stated fraction of the population and ensuring, based on available data, that those vaccinated persons are susceptible.
In such situations, there are enough susceptible children to sustain widespread infection, leading to outbreaks of paralytic disease.
Simply put, exposure of susceptible animals to enough infectious material will cause disease, as demonstrated in a variety of animal models.
According to the behavioural model proposed by Andersen, 10 need factors are fundamental to healthcare seeking behaviour, that is, one should perceive a condition as susceptible and severe enough before seeking care to gain benefits.
The initial peak in annual CoV and AstV prevalence observed in our study was probably due to the formation of a contiguous population of sufficient size and density, bringing together enough susceptible bats to establish a critical basic reproductive rate of infection (28, 29 ).
The products of heavy metal, collapsed family structures and inertia, they're mischievous and susceptible, and not gumptious enough for real misbehavior.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com