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Our findings may have important implications for understanding host susceptibility to develop severe chronic infectious disease.
Environmental stress is among the most important contributors to increased susceptibility to develop psychiatric disorders.
Genetically determined differences in activity of this enzyme could modulate individual susceptibility to develop cancers.
Genetic and environmental factors jointly determine the susceptibility to develop Multiple Sclerosis (MS).
Cancer treatments and malignancy-related immunosuppression could explain the higher susceptibility to develop nosocomial infections in the onco-haematological population.
Therefore, no evidence for an association of CISH promoter variants and susceptibility to develop T1D was detected.
Polymorphisms in tumor suppressor genes might contribute to the individual susceptibility to develop different types of cancer.
Using a CSD rat model, we investigated if valproate and topiramate lower the susceptibility to develop CSD by inducing changes in brain DNA methylation.
In the present study, we addressed the question if CISH SNPs are associated with susceptibility to develop T1D and/or with age at onset and disease severity.
Subjects with familiar risk of migraine, showed reduced habituation of nociceptive blink reflex as a sign of their susceptibility to develop migraine under precipitating factors [30].
These autosomal dominant alleles are statistically associated with susceptibility to develop RD.
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