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b Peak activation in a cluster of at least 50 voxels in which the difference survived a threshold of P < 0.001 in a random-effects analysis.
Along the same lines, Árnason (1999) and Urioste et al. (2007) have proposed a bivariate linear-threshold model that can be used to analyze whether an animal survived (a threshold trait) and how long it took until death (a linear trait).
All clusters survived a threshold for the conjunction of P < 0.001 (uncorrected for multiple comparisons; right lingual gyrus: 5 voxels; left middle occipital gyrus: 59 voxels; right middle occipital gyrus: 33 voxels; medial frontal gyrus: 6 voxels; left posterior superior parietal lobe: 13 voxels; and right posterior superior parietal lobe: 8 voxels).
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To control the type I error rate, Gaussian random field theory was applied to assign corrected significance levels to clusters of voxels surviving a threshold of Z>3.0; all imaging results presented in this paper are based on a cluster-level criterion of p<.05 [42], [42].
Concerning hippocampal activations, we only report activations surviving a threshold of p<0.001.
The TVAs identified by the independent functional localizer were located as expected along the upper bank of the superior temporal sulcus (STS); 3 clusters were identified surviving a threshold of 6.5 (threshold T value for a P < 0.05 familywise error [FWE] corrected, see Table 1 and Fig. 2 a ).
Since in this analysis it is assumed that all contrasts included in the conjunction show consistent effects, for the conjoint effect to be significant all contrasts have to survive a threshold that decreases with the power of the number of contrasts included ('global' conjunction in SPM terminology, Friston et al., 2005).
Correction for multiple comparisons was performed using distribution approximations from the theory of gaussian fields (Worsley et al. 1992) at the cluster level (P ≤ 0.01 corrected), after forming clusters of adjacent voxels surviving a threshold of P ≤ 0.01 uncorrected (Friston et al. 1996).
We report clusters that survived a voxel threshold of p≤0.001 uncorrected and a random field cluster threshold of p≤0.05 corrected for the entire brain, unless otherwise stated.
We report results that survived a voxel threshold of p≤0.001 uncorrected and a random field cluster threshold of p≤0.05 corrected for the entire brain.
The amygdala activation also survived a higher threshold of k = 20 and FDR correction (at P<0.001).
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