Note also that, in the dorsal disc (the Apterous territory), chip e55 mutant clones barely survive (indicated by asterisks in the merge in G ), compared to ssdp L7 mutant clones that appear to grow normally, like pygo S123 mutant clones; however, in the absence of Apterous, i.e. in the ventral compartment, chip e55 mutant clones grow normally (see clone marked by arrow in E ).
In contrast, myoblasts lacking all three Rb family members do not efficiently fuse or survive, indicating that expression of at least one Rb family protein is essential for these processes.
Loss of both Notch and Egfr function caused all placode cells to become IPC NBs and survive, indicating that commitment to NB fate nullified the requirement of Egfr activity for placode cell survival.
But another group of caterpillars whose houses were decorated with similar-sized glass beads all survived, indicating that skippers shoot frass to avoid attracting predators.
Interestingly, when grown on the medium with low K+ level, only the E. coli transfected with OsGLR2.1 and OsGLR3.2 survived, indicating a complementation of OsGLR2.1 and OsGLR3.2 to the K+ uptake-deficiency of LB650 (Additional file 7B).
In our conditions, however, only one of the seven R mutants (BmH38RwbkD) survived, indicating that complement sensitivity is a usual characteristic of B. melitensis R mutants whose contribution to attenuation cannot be dismissed.
When added prior to Day 7 (D7), no cells from either the parental R1 or clonal lines survived, indicating that the ncx1 promoter was not activated prior to CM commitment and differentiation.
Interestingly, this study demonstrated that independent of Breeding Protocol, there was a sizeable discrepancy between litter size (i.e. number of pups born) and litter maintenance (i.e. number of pups survived), indicating that all litters were subjected to early death via dam-mediated mechanisms such as cannibalisation or neglect.
During the subsequent observation period, all vaccinated animals survived indicating that they were robustly protected against a lethal challenge with SC35M.
The higher concentration of temozolomide (800 μ) killed all A2780 cells but around 15% of CP70-B1 and 60% CP70-A2 cellsurviveded, indicating that both p53 and MMR have significant roles in temozolomide-induced cell death.
Although our study design did not allow us to demonstrate any direct association between the treatment applied and late levels of presepsin, we speculate that the drop in presepsin levels in patients who survived indicates a beneficial effect of the treatment by reducing the activity of the bacterial infection or by controlling its systemic reactivity.
