Sentence examples for survival role from inspiring English sources

Again, these results argue against a mandatory cell survival role of a transduction pathway that should convey signals to VDAC.

These findings, altogether, clearly establish that hyperactivation of basal autophagy plays an essential survival role in Tzb-refractory TzbR cells re-challenged with Tzb.

The need for this dual and sequential regulation of BAG3 suggests a selective survival role of BAG3 in the cancer cells.

Several in vitro studies have demonstrated a survival role of BAFF on transitional as well as mature B cells [16], [38].

If PI3K/Akt plays an important survival role in rCMECs, inhibition of PI3K/Akt should potentiate H2O2-induced apoptosis; indeed this was observed.

Different experimental approaches, performed by other groups, were also suggestive of a survival role of BAFF-BAFF-R signaling in mature B cells.

Tissue specific deletion of Survivin in thymocytes causes mitotic defects and cell death (Okada et al., 2004), clearly indicating that the pro-survival role of Survivin in vivo.

The MTT assay was used to verify the pro-survival role of siHRK.

However, excess free AMF/PGI also reduced the cytotoxic effect of free paclitaxel suggesting that it may generally exhibit a pro-survival role [30].

These results suggest that ATF2 has a strong pro-survival role, and its absence leads to Caspase 3 dependent cell death at least in early-born abducens neurons.

In fact, in the Rpl24-deficient mouse embryos, p53 plays pro-survival role, which was suggested to depend of p53 targets inducing cell cycle arrest [27].