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Table 2 shows the HRs and 95% CIs of 1.34 (95% CI 0.85 to 2.12) for after-hours cases relative to working hours cases for survival extending to 30 days (our primary study outcome) and 1.18 (95% CI 0.81 to 1.72) for survival extending to 1 year.
The small number of stage IV patients also resulted in a wide confidence interval for the univariate hazard ratio for overall survival, extending upwards to over 2, so our data were not incompatible with FIGO stage as a prognostic indicator.
Even more encouraging are results arising from the addition of new biological agents, such as bevacizumab, cetuximab, and panitumumab; using various combinations of these drugs achieves median overall survival extending beyond 2 years for patients with metastatic disease (Hurwitz et al, 2005; Wadhawan et al, 2009).
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Intraspecific competition among larvae within the same bean can result in reduced survival, extended development time, and reduced adult size at emergence (e.g., Messina 1991).
Censor follow-up at one year, if imputed survival extends to beyond one year.
In some case reports, survival extended to 12 months after comprehensive treatment [ 22].
However, combination therapy with BKM120 and PD0325901 led to a survival benefit, with median survival extended to 16 days (Fig. 5D).
These are considered incurable, but because of the indolent clinical course, they have a reasonably good overall prognosis with a median survival extended to 10 15 years.
Moreover, in mice xenografted with T-ALL cells in which IL-18R expression is reduced, leukaemia development is delayed and animals' survival extended.
The survival curves for septic mice clearly attest to the prolonged survival in NOS3−/− mice with median survival extended to 70 h from 29 h in WT mice (Fig. 1a).
Continuous dosing was particularly effective in the RENCA model, with median survival extended to 33 days or beyond, compared to a median survival of 23 days in vehicle-treated mice (Fig. 4d).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com