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This survival data provided physiologic evidence that ambient oxygen can indeed promote tumorigenesis in a setting of reduced genomic protection such as found in p53−/− mice.
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Third, survival data provide a unique insight into the natural history of these disorders and help to validate functional assessments in relation to prognosis.
While we employed a comprehensive set of statistical tests, including those sensitive to the detection of differences in early survival, our data provide little evidence to support the tenet that the FGFR4 Gly388Arg polymorphism is a clinically useful marker for lung cancer prognosis.
Study design: Mortality data were derived from the National Institute of Statistics while incidence and survival data were provided by an ad hoc survey carried out over the period 1978 1982 and by the Umbrian Population-Based Cancer Registry operating since 1994.
When only crude survival data were provided, odds ratios (ORs) and standard errors were calculated.
A description of survival data is provided in Supplementary Table 1.
Corresponding raw miRNA expression data, sample age, and survival data are provided in Datasets S1 S3 in Additional file 2, Additional file 3, and Additional file 4, respectively.
Survival data were provided for all patients and as expected, the majority of patients (80%) had died with over three-quarters of patients within each trial having died.
The pooled data provided survival information of 26 591 most recent live-born infants within the 5-years prior to each interview.
The survival analysis uses the clinical data provided by the TCGA.
The derived survival data then provide a quantitative measure of the effectiveness of guideline adherent cancer care in the routine setting and extend the data available from clinical trials.
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