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Long-term survival analyzed with the Kaplan Meier method was significantly greater in the NIV group (p = 0.016) (Fig. 1).
Cell survival analyzed by quantitative real time PCR for human GAPDH and capillary density measured by immunostaining showed consistent results.
In parallel experiment cells were fixed with 4% paraformaldehyde and cell survival analyzed 24 h later.
7, 8, 25, 26 The presence of positive non-SNs is per se highly negative prognostic factor for patient survival analyzed recently by other authors.
To this aim adeno-associated viruses (AAV) expressing p75 shRNA or scramble shRNA were bilaterally injected into the striatum of wild-type and HD mice, corticostriatal slices obtained and cell survival analyzed following BDNF treatment.
The ten year metastasis free survival analyzed with the log-rank test showed a highly significant difference between (i) the G2I-3 and G2I-2 groups (hazard ratio: 3.24 [95CI: 1.76-5.96] p = 6.7x10-5 and (ii) a borderline significant difference between the G2I-1 and G2I-2 groups (hazard ratio: 2.29 [95CI: 0.90-5.78] p = 0.072).
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Survival analyze was performed using Cox proportional model with time-dependent covariates to assess the effect of the variables of interest on overall survival.
The effect of vaccination on survival was analyzed using survival analysis (Cox proportional hazard models).
The consequences of Acm treatment on cell survival were analyzed through clonogenic survival analysis.
Progression free survival and overall survival were analyzed using Kaplan-Meier and Cox proportional hazards models.
Time to event outcomes (progression-free survival and overall survival) were analyzed using Kaplan-Meier curves.
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