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Table 1 illustrates the discrepant results of past surveys of expression of BDNF protein and/or mRNA in the OE and olfactory bulb (OB).
These results are made possible due to broad surveys of expression and the comprehensive characterization of the yeast genome with deletion mutants.
This is higher than the GEL50 of 1.51 reported for the male experiment [ 18], but still within the range reported for similar surveys of expression polymorphism in Drosophila and other species [ 2].
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Here we present the results from a large-scale porcine survey of expression profiles of 26.877 microarray cDNAs representing approximately 20.000 genes in 23 healthy tissues.
By utilizing a comprehensive survey of expression characteristics of proteins as well as of their immediate network localities in several datasets, our study confirms the notion of dynamic modularity in the eukaryotic protein interaction network.
A survey of expression levels revealed that the novel splice isoform and non-Augustus gene models were highly expressed.
It is important to note that these RT-PCR investigations do not represent an exhaustive study of CLDN gene expression, but rather a survey of expression in a large number of different human tissues.
In sum, our wide-ranging survey of expression profiles and generic metric of expression divergence allowed us to identify both global and local aspects of regulatory evolution and relate these to sequence divergence.
Supporting these data, Lu et al. [ 21] also detected miR-21 as being expressed in pulmonary macrophages of A. fumigatus-challenged mice and in a survey of expression, the levels of miR-21 in macrophages exceeded that of epithelial or fibroblast cell lines.
Further, we made a comprehensive survey of expression patterns for the hh-related genes and found that all of these genes are expressed in one or a few of the following cell types: hypodermis, seam cells, excretory duct and pore cells, vulval epithelial cells, rectal epithelial cells, arcade cells, pharyngeal muscle or marginal cells, support cells of sensory organs and neuronal cells.
Microarray based surveys of gene expression allow detailed surveys of gene expression across a wide variety of experimental perturbations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com