Sentence examples for surveillance cell cycle from inspiring English sources

By linking genome stability surveillance, cell cycle, and energy metabolism, the ~370 kDa Serine (Ser)/Threonine (Thr) kinase ataxia telangiectasia mutated (ATM) has begun to emerge as a central DNA damage checkpoint that connects cellular bioenergetics with cancer predisposition and aging [ 1- 4].

P53 is a key regulator of stem cell homeostasis that impacts an array of cellular functions including genomic surveillance, cell-cycle regulation and apoptotic and inflammatory response.

It is interesting to learn how melanoma cells can still manage to grow vigorously (as indicated by the 12.6-fold increase of PCNA expression level) despite the surveillance of cell cycle progression checkpoints and apoptotic pathways in the context of such drastic alterations in multiple pathways.

First, defective ribosomes may trigger specific developmental defects through their participation in surveillance mechanisms at cell cycle checkpoints.

Despite that uncertainty, it is acknowledged that aneuploidy is a consistent feature of cancer cells associated with chromosomal mis-segregation and CIN with defects centered within mitosis, cell cycle surveillance, the centrosome cycle and the spindle apparatus [65, 66].

These data imply that Bub3 may contribute to the cell cycle surveillance as a checkpoint protein in mammalian meiosis.

As part of the cell cycle surveillance system, the DNA damage and spindle checkpoints protect the cell from genomic instability.

Spindle assembly checkpoint: surveillance mechanism that halts cell cycle progression until all chromosomes have attached to the spindle.

This may alert a 'salvage' strategy like checkpoint surveillance to stall the cell cycle or a 'disposal' mechanism like apoptosis to eliminate irreparable cells.

Recently, we reported the existence of a cell cycle surveillance mechanism or 'checkpoint' in S. cerevisiae that safeguards the inheritance of functional ER by the daughter cell (Bicknell et al., 2007; Babour et al., 2010).

Our results suggest a novel cell cycle surveillance mechanism that monitors nucleosome assembly without involving the DNA repair pathways and exerts its effect via suppression of CDC25 phosphatase String expression.