Sentence examples for surrounding modification from inspiring English sources

Moreover, as discussed in the revised text, sets including only closest non-modified serines provide an even better control for artifacts that could be caused by specifics of regions surrounding modification sites.

While they specifically recognize specific modifications, their interactions are context independent, although residues surrounding the modification sites confer some specificity.

However, Valentin Tilloy and collaborators argue that given the feasibility of classic methods and the public hesitation surrounding genetic modification, artificial selection still holds great promise for the generation of commercially relevant organisms (Tilloy et al. 2014).

Expression of specific genes is not only affected by the epigenetic levels of the whole genome but also by the surrounding epigenetic modifications.

One of the underlying reasons for the success of these folds in acquiring new functions is that they hold a wide active site that can accommodate complex and multiple substrates simultaneously and the presence of many surrounding loops, modifications of which can alter the chemical and catalytic properties of the protein, its substrate/product profile, or cofactor-binding properties.

In E. coli, KsgA contacts rRNA regions in the 30S subunit that surrounds the modification sites in H45 including H11, 24, 27, 28 and 44 (Supplementary Figure 5) and these interactions are proposed to be important in preventing premature interactions of pre-30S particles with the translation machinery.

Hence, understanding the complex processes surrounding ECM production, modification and remodeling, and relating these processes to physiological changes in the biochemical and biomechanical properties of the ECM, are key to determining how microenvironmental changes influence cellular responses.

It is of note that the common features surrounding O-GlcNAc modification sites described here and before [ 9], which are apparent in the primary structure of a protein, can also be achieved or constituted in the secondary structure of proteins by residues present distantly from each other.

In the case of the PPARγ agonist cellular system, the key structural modifications surrounding ligand binding were successfully detected and the tendencies of impact were examined.

In a ligand-dependent receptor-mediated cellular system (or ligand cellular system), key structural modifications surrounding ligand binding are expected to cause outliers.

Taken together, these correspondences clearly point out that the top-ranked ES symbols are the key structural modifications surrounding molecular binding.