Given that no reimbursement authority has issued guidelines about which technique of economic evaluation is appropriate to calculate the cost-effectiveness of a biosimilar and given that there may be uncertainty surrounding relative effectiveness (cfr. supra), submissions to reimbursement authorities may include a cost-minimization analysis as well as a cost-effectiveness or cost-utility analysis.
The wide spread of effectiveness results shown in the scatter plot illustrates that the results are associated with considerable uncertainty surrounding key effectiveness and outcome parameters.
Although the effects of resveratrol in rodents have shown significant improvements, questions have emerged surrounding the effectiveness on humans.
They discuss a new trend in character role model figurines, which some believe perpetuate racial and ethnic stereotypes, and debate issues surrounding the effectiveness of these role models.
However, for all the evidence surrounding the effectiveness of caffeine, researchers have yet to come to a unified agreement as to exactly how it works.
But it is doing its best to capitalise on the recent controversy surrounding the effectiveness of technology in schools and the wider impact on young people.
Regardless of the debate surrounding the effectiveness of its work and management control, its clients no longer have the services they did, and its staff, volunteers and trustees have been left with no idea of what the future holds.
The purpose of this paper is to systematically review literature surrounding the effectiveness of speech-language pathology intervention for the management of UVFP in adults.
Moreover, both inside and outside SAC, there had been much controversy and debate surrounding the effectiveness of the Alzheimer's drug, called bapineuzumab, leading up to the July 2008 release of the companies' clinical results.
While it dealt with the many questions surrounding the effectiveness of these drugs in treating depression, it sidestepped some recent studies suggesting that these drugs are -- over the long term -- harmful to the brain.
