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Metastatic infiltrating tumor cells were identified by several criteria including: high ratio of hematoxylin relative to eosin, surrounding abnormalities in lung structure, abnormal shape/size of nuclei and/or presence of abnormal mitotic spindles, and differences in cell shape and size, with ≥ 1 infiltrating tumor cells counted as a metastatic event.
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The circumstances surrounding such abnormalities remain unclear.
To address this problem, we propose a tracking method for capsule endoscopy using the surrounding features of abnormalities.
The one thing he did manage to pick up was that 'there was a hideous aura of criminality and degeneracy and abnormality surrounding the matter'.
Antony Grey, a secretary of the Homosexual Law Reform Society, wrote of "a hideous aura of criminality and degeneracy and abnormality surrounding the matter".
d SWI minIP: increased visualisation of markedly hypointense foci surrounding the white matter abnormalities which correspond to multiple cerebral microbleeds.
Ever since the Chernobyl accident in 1986, that contaminated vast areas in surrounding countries with radiation, abnormalities and birth defects have been reported in human populations.
According to Ellsworth et al. [ 30], genetic abnormalities have been observed in histologically normal epithelial cells surrounding breast carcinomas and that abnormalities of tumourigenic importance could accumulate in these cells.
Genomic alterations observed outside the histologically visible tumour margins could result from pre-existing fields of precursor cells in which cancer develops; alternatively, the tumour could have an effect on the surrounding tissue, or the observed abnormalities could reflect both of the above abnormalities [ 15].
Additional MRI including axial STIR (b), post-gadolinium axial fat-suppressed (c) and coronal (d) T1-weighted images showed extensive inflammatory signal abnormalities and hyperenhancement surrounding the anus, involving the right sphincter complex and obturator internus muscles, and extending to the ischioanal fossa.
The presence of such abnormalities in tissues surrounding tumors is called field cancerization or field defect [ 13].
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