Sentence examples for surrogate qualifications from inspiring English sources

Surrogate qualifications differ slightly by agency, but Ms. Brisman's criteria are typical: The carrier must be between the ages of 21 and 44, must be a nonsmoker, must live in the United States and must have given birth to at least one child.

Formal evaluation of surrogacy status using a standardised framework, such as the BSES3, can be used to begin discussions on a surrogate biomarkers qualification process [ 2].

Qualification as surrogate endpoints requires significant resources and will, in many cases, only be possible in a concerted effort of academia, industry and regulatory authorities, as proposed for example by the Biomarkers Consortium (http://www.biomarkersconsortium.org), a public-private partnership managed by the Foundation for the National Institutes of Health in the USA.

The more clinical trials that incorporate potential surrogates, the sooner the discovery and qualification of a surrogate marker can be expected.

Qualification of each surrogate response biomarker (e.g. the proliferation marker FLT) will be necessary for quantitative studies to demonstrate the clinical efficacy of new agents.

To provide multi-centre validation and qualification of pharmacodynamic imaging biomarkers and surrogate endpoints.

The agency may also have additional qualifications, however, which could make becoming a surrogate more difficult.

Here, participants with an education up to secondary school level were more likely to have a positive perception towards surrogate consent than those who held a degree-level qualification.

In this regard, the qualification of novel biomarkers that may be used as surrogate end points also requires long follow-up times.

Qualification is necessary for use of a biomarker as a surrogate endpoint.

Most recently the Institute of Medicine of the National Academy of Sciences in the USA has put forward an evaluation scheme for biomarkers, looking at validation (assay performance), qualification (assessment of evidence), and utilisation (the context in which the surrogate is to be used).