Sentence examples for surrogate pathway from inspiring English sources

The resultant sensitization effect unmasks the surrogate pathway, giving a phantom sensation.

These findings suggest that the thalamic representation of the amputated limb was remapped to a surrogate pathway from the stump of the missing limb, presumably via learning.

In particular, if the primary pathway is part of a pain pathway then the referred phantom sensation may give rise to phantom pain if the surrogate pathway or its referred central representation in the pain pathway is hypersensitized.

In contrast to the inhibition/disinhibition hypothesis of unmasking, the present theory postulates that the surrogate pathway may be normally desensitized and, hence, rendered ineffective by the primary pathway.

Deafferentation abolishes ("gates off", see Sect. 4.1) the primary pathway and its sensory dominance, allowing the intact surrogate pathway to strengthen over time through synaptic plasticity processes such as LTP.

In keeping with the notion of unmasking of preexisting pathways, we propose a two-tier nonassociative learning model of somatosensory organization, with the primary and referred sensations being mediated by a primary pathway and a latent surrogate pathway, respectively (Fig. 2B).

In addition, in order to form a baseline measure, we created random gene sets as surrogate pathways by keeping KEGG pathway designations but doing a full permutation all genes (i.e. replacing each gene in a pathway by a randomly selected gene).

Therefore human transformed GC B cells (BL2) can be defined as a suitable in vitro model used as surrogate for pathway activity.

The primary and surrogate (secondary) pathways are functionally equivalent to the primary and secondary pathways of nonassociative learning (Fig. 1A).

We studied 24 reports of SPINK1 N34S in CP (2,421 cases, 4,857 controls) using reported etiological factors as surrogates for pathways and multiple meta-analyses to determine the differential effects of SPINK1 N34S between alcoholic and non-alcoholic etiologies.

Western blots for phosphorylated molecules were used as surrogate markers for pathway activation.