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The positron ranges in water, as a surrogate of human tissue, are from the National Institute of Standards and Technology web site [14].
A substantial amount of our knowledge regarding the underlying molecular mechanisms that contribute towards the pathogenesis of CM comes from studies using the P. berghei ANKA murine model of experimental cerebral malaria (ECM), a well-established surrogate of human CM.
These tissues can serve as an in vitro surrogate of human skin that have been previously used to study the capacity of fibroblasts to support the growth and differentiation of the surface epithelium [30], [31].
Genome-wide transcriptional profiling of the brain tissue during experimental cerebral malaria (ECM ) caused by Plasmodium berghei ANKA parasites in mice, a well established surrogate of human cerebral malaria, has been useful in predicting the functional classes of genes involved and pathways altered during the course of disease.
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To determine whether this link exists, we attempted to transmit rat HEV to rhesus monkeys, a surrogate of humans that are highly susceptible to mammalian genotypes 1 4, including swine HEVs (26 – 26 ).
Being able to extract as much statistical information as possible from the available images, computational model observers can be used as convenient and objective surrogates of human beings to predict and/or define their expected performance [6, 8].
Leading-edge culture devices have been developed that represent more relevant, organotypic in vitro surrogates of human liver and recreate the three-dimensional, multicellular architecture and hemodynamic properties of the liver.
Part of the problem may be the relevance of animal models as surrogates of human sepsis.
Several oligosaccharide fractions were synthesised as possible surrogates of human milk oligosaccharides.
Langley concluded that relying on animal surrogates of human illnesses is a flawed approach in science.
Transgenic mouse models of AD have been designed to act as surrogates of human pathological processes of neurodegeneration observed in AD (neurofibrillary tangles and senile plaques).
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