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The pet monkey is chained... they are supposed to be surrogate humans, like court jesters and keep within certain rules of cute monkey behavior.
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In this study, a surrogate human sensor (SHS) was developed to establish a linkage between human skin surface and SHS with the surrounding environments.
ZIKV infection of explants represents a surrogate human model for evaluating protection against transmission by antibodies in vaccine recipients and passive immune formulations and novel therapeutics.
Nim was dressed in diapers and clothes, he ate at a high chair, had books and toys -- and a very large surrogate human family.
Humanized mice able to reconstitute a surrogate human immune system (HIS) can be used for studies on human immunology and may provide a predictive preclinical model for human vaccines prior to clinical trials.
In recent times, a shift has occurred toward creating humanoid machines that attempt to mimic human beings [22], be it for surrogate human interactions [21], [23] [26], "intuitive or natural" human computer interactions [27], [28] or more broadly cognitive and behavioral cooperation between humans and machines [27], [29] [35], including in rehabilitation settings [36] [39].
This is, to our knowledge, the first study of miRNA expression profiling extensively encompassing the duration of neurogenesis from surrogate human stem cells, through to neural precursors and in particular highlights the differences in miRNA expression of the terminally differentiated cell types (i.e., astroglia and post-mitotic neurons) originating from a common pool of progenitors.
Since most infections in X-HIGM patients are chronic, C57-CD40L−/− mice will help to study the immune response elicited against human or surrogate human pathogens and to implement treatments that hopefully will help pathogen clearance in X-HIGM patients.
The workshop participants also concluded that the laboratory animal is an adequate surrogate for humans because many of the biologic and behavioral mechanisms underlying these neurologic functions are shared between humans and laboratory animals.
To determine whether this link exists, we attempted to transmit rat HEV to rhesus monkeys, a surrogate of humans that are highly susceptible to mammalian genotypes 1 4, including swine HEVs (26 – 26 ).
We therefore wanted to measure the level of control of viral transgene expression that could be achieved in primary human hepatocytes as a surrogate for human liver.
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