Sentence examples for surrogate host from inspiring English sources

They would then swap this nucleus into an egg cell from the animal's closest living relative and implant the egg into a surrogate host.

This approach demonstrates that D. discoideum is a suitable surrogate host for preliminary high-throughput screening of antivirulence agents and that PPK1 is a suitable target for developing novel antivirulence compounds that can be further validated in mammalian models.

The in vivo efficiency of ribozyme was evaluated in Saccharomyces cerevisiae as it can act as a surrogate host for replication of the MYMIV-DNA and lacks RNAi machinery.

Furthermore, the lateral transfer of 'silent' (not expressed under standard laboratory conditions) secondary metabolite pathways or metagenomic DNA into surrogate host strains is expected to yield new, potentially bioactive compounds.

Recently, the genetically engineered strain Bacillus subtilis KE30 has been reported as an excellent surrogate host for the heterologous expression of an entire nonribosomal peptide synthetase (NRPS) gene cluster.

To facilitate the discovery of new therapeutics for Burkholderia pseudomallei infections, we have developed cellular reporter screens for inhibitors of B. pseudomallei targets in the surrogate host Pseudomonas aeruginosa.

In Los Angeles, some parents are afraid to claim their children and turn to surrogate hosts who might be cruel to the children or force them to drop out of school and work, said Mercedes Núñez Roldán, a manager for released youth at an Esperanza center in Los Angeles.

This conservation made non-vertebrates amenable surrogate hosts for studying mammalian pathogenesis and added the benefit of enabling broadly conserved virulence factors to be identified.

There are a number of potential surrogate hosts.

Use of animals as surrogate hosts for dose response assessment in humans can be misleading, as there is little quantitative knowledge of how to translate susceptibility across host species and/or inoculation routes.

Experimentation using surrogate hosts and S. enterica serotypes (e.g. S. Typhimurium) suggests that tissue invasion occurs predominantly through M cells on Peyer's patches in the terminal ileum [ 16, 17].