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Just as important, Grimes could serve as an appealing national surrogate among a younger generation of women who don't know the Clinton story.
In the first questionnaire, panellists were asked to choose the most important characteristics defining a surrogate among six proposals, to give advantages and drawbacks of the surrogates, and to answer questions about their validation and use.
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Distributions of the formal and surrogate criteria among all patients without diabetes or CHD and among those with at least three criteria measured are shown in Additional file 1: Table S2.
Therefore, a feline calicivirus (FCV) is often used as its surrogate to, among other things, test alcohol-based handrubs (ABHR).
Although randomised controlled trials have demonstrated that preoperative glucocorticoids may improve postoperative surrogate outcomes among patients undergoing major liver resection, evidence supporting improved patient-important outcomes is lacking.
24 Although the above studies have demonstrated that preoperative glucocorticoids may improve surrogate outcomes among patients undergoing major liver resection, evidence supporting improved postoperative patient-important outcomes is lacking.
We recently developed a printed decision aid to assist the process of shared decision making among surrogate decision makers of critically ill patients and their providers facing a decision about the provision of prolonged life support [8].
For diagnosis, the ratio of pulse oximetric saturation to fraction of inspired oxygen (SpO2/FiO2) was used as a validated surrogate for PaO2/FiO2 among patients without an arterial blood gas measurement at the time of ARDS diagnosis: SpO2/FiO2 = 64 + 0.84 × (PaO2/FiO2) [19].
Since laboratory culture of HuNoV is difficult, the feline calicivirus (FCV) is often used as its surrogate in testing, among other things, microbicides [9], [10].
We identified four factors likely to have a strong influence on the apparent effectiveness of surrogates: (1) the choice of surrogate; (2) differences among study regions, which might be large and unquantified (3) the test method, that is, how effectiveness is quantified, and (4) the test features that the surrogates are intended to represent.
A Steiger t test was used to compare correlation coefficients among surrogate indices.
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