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It has become clear in recent years that even one success can have a surprisingly stimulating effect on an entrepreneurship ecosystem by igniting the imagination of the public and inspiring imitators.
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This may explain why the WhiB7 (=WblC -dependent response of M. tuberculosis to antibiotics was surprisingly stimulated by reducing conditions (added dithiothreitol), but not by oxidative stress induced by the thiol oxidant diamide (Burian et al., 2012).
DMSO surprisingly stimulates the wild-type PML enzyme, but has little effect on Dieselzyme 4. We also compared the organic solvent tolerance of Dieselzyme 4 to the tolerance of the B. cepacia lipase.
Overexpression of Myc in the epidermis not only stimulates proliferation, as in virtually all cell types (Eilers & Eisenman, 2008), but also, surprisingly, stimulates differentiation.
Surprisingly, R1881 stimulated AR recruitment was not affected by RSV treatment although the AR transcriptional activity was reduced dramatically by RSV treatment, as shown in Figure 5 and Figure 6A.
Surprisingly, RFC stimulated Ubc9-dependent sumoylation at K127 even in the absence of Siz1 (see also Supplementary Figure S2).
The H1/CA peptide pool stimulated surprisingly high amounts of CTLs, around 3 5% of total CD8 T cells were specific for H1, whereas the N1-specific peptide pool used as a negative control, did not induce significant levels of CD8 T cells (P>0.05), Fig. 4B).
The high-fat diet did not significantly influence hypothalamic AGRP in this study, but surprisingly adrenalectomy slightly stimulated hypothalamic AGPR mRNA levels (Fig. 5B).
We found that the conidia bound to macrophages in a dose-dependent fashion, yet surprisingly failed to stimulate the production of TNF, even at high multiplicities of infection (moi).
Surprisingly, EPA-dosed adipocytestimulateded a significantly greater invasive stimulus than either negative control (P=0.00543 and 0.0023) achieving levels similar to 3 μg ml−1 free AA (16 927.6±928.7 vs 16 236±316.86 P=0.6887).
Surprisingly, phenol stimulates the latter conversion rather than inhibiting it, an effect that may play a role in the in vivo myelotoxicity of benzene.
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CEO of Professional Science Editing for Scientists @ prosciediting.com