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FSP1 mRNA decreased, as expected, in both normal fibroblast cell strains and in CAF-74 cells, but surprisingly increased in CAF-43 spheroids (Figure 2D).
SQSTM1 protein expression was decreased by ischemic insult in WT mice but, surprisingly, increased in arrb1 −/− mice (Fig. 5E).
The synthetase: transferase activity ratio of the new enzyme GS2b is surprisingly increased in relation to all the other Medicago truncatula GS isoenzymes (cytosolic or plastidic) [ 20].
31 Furthermore, we found that hepatic triglyceride uptake was surprisingly increased in ApoC3Tg mice fed either the RC or HFD despite the absence of hepatic steatosis when the ApoC3Tg mice were fed the RC diet.
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We observed by Western blot analysis and by Flow cytometry that MET inhibition by different MET small molecule inhibitors surprisingly increases in a dose-dependent manner total MET levels in treated cells.
In contrast to monocyte-like RESMAC, the proportion of apoptotic cells was not surprisingly increased after in vitro culturing.
However, Rb2/p130 expres-sion surprisingly increased during senescence in MSCs [ 92].
Surprisingly, increased body weight gain in Sub did not translate into higher fat pad weight.
Surprisingly, increased proliferation of HSCs in Smurf2-deficient mice did not lead to premature stem cell exhaustion.
Intriguingly, sFrp-2 was sufficient to protect CMs from hypoxia-induced apoptosis and surprisingly increased β-catenin levels in CMs.
As expected, I κB α levels decreased after LPS/GLN injection, but surprisingly, increased 6 h after injection in CerS2 null mice.
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