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Surprisingly, differentiated ectoderm germ structures were not found in Twin-DS-iPSC-derived teratomas (Fig 3A lower panel).
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Surprisingly, in differentiated SH-SY5Y cells, these phosphorylation events did not occur after etoposide treatment.
Most surprisingly, injection of differentiated cells into CsA-treated LO U/crats resulted in 11 of 18 cases in teratomas (Table 2).
Surprisingly, B6-S3Y118F mESCs differentiated after administration of 50 ng/ml GCSF for 24 hours (Fig. 2A, right panel).
Surprisingly, although the differentiated parts of the hair follicle, such as suprabasal outer root sheath, upper companion layer, upper inner root sheath or the hair fiber, are heavily keratinized structures, all of them are free of K1/K10.
More surprisingly, even cultures of hESC differentiated for up to 4 months had no detectable immune response to TLR2 (Gram positive) or TLR4 (Gram negative) activation.
In contrast, a surprisingly high frequency of morphologically differentiated sex chromosomes occur in Notothenioidei, a perciform fish group endemic to Antarctic waters [ 14, 15].
Since a high proportion of people are hosting bacteria in their urinary tracts, asymptomatic bacteriuria (ABU) is surprisingly common, which clearly should be differentiated from symptomatic urinary tract infection (UTI).
In summary, although thick-lipped species are common in cichlid radiations, and A. citrinellus and A. labiatus are morphologically and ecologically clearly differentiated, they remain genetically surprisingly indistinguishable (Additional file 2, Figure S2).
Surprisingly, Pvrl4 expression is also reduced in differentiated AEC keratinocytes, even though its expression is not altered in p63-depleted keratinocytes or epidermis.
Surprisingly, lipomas were larger than the well-differentiated liposarcomas.
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