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When further restricting these calculations to missense mutations, we excluded sample PMBL.29 that harbored only a sense mutation (c.2394 C>T; p.I798I); the overall frequency of missense KIT mutations in PMBL (4 of 32 different samples) surmounts to ~12.5%.
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The physical, technical and regulatory hurdles that would have to be surmounted to make such an extension happen are tremendous.
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The problem has surmounted to be about time.
There are issues of trust and bias that need to be surmounted to provide the collaborative environment that this process would need.
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Mrs. Arroyo has also failed to surmount political opposition to the sale of government-owned companies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com