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Steroid-associated osteonecrosis (SAON) often requires surgical core decompression (CD) in the early stage for removal of necrotic bone to facilitate repair where bone grafts are needed for filling bone defect and avoiding subsequent joint collapse.
Additionally, surgical core markers (duration of surgery and duration of CPB) pointed to a significantly higher operative risk.
Surgical procedures and surgical core data are shown for patients undergoing elective on-pump cardiac surgery with or without a perioperative infusion of bicarbonate.
Seven patients were given conservative therapy, including limited weight-bearing, for a period of three weeks after the initial detection of BMES, whereas one patient underwent surgical core decompression twice.
Trials investigating the auxiliary facets of the intervention are valuable, but studies evaluating the surgical core of an innovative procedure (whether a new procedure or a modification of an established procedure) are crucial.
With the exception of a lower prevalence of a history of myocardial infarction (18.6% vs. 26.3%) and a lower preoperative use of intravenous heparin in the BIC group, the study cohorts were highly comparable regarding baseline demographics, surgical procedures, and surgical core data (Table 1, 2, and 3).
Similar(54)
All samples except for two were non-surgical core biopsies as surgery is not a standard procedure in SCLC treatment (usually diagnosed in advanced stages).
Core biopsies from 81 patients prior to chemotherapy (64 matched surgical and core biopsy; and 17 core biopsy only) and tumour samples from 79 patients after chemotherapy (64 paired as above and 15 surgical) were arrayed into two TMA blocks.
These include surgical excision, core biopsy, fine needle aspiration biopsy or mammographic surveillance.
Therapy options are conservative treatment (reduction of weight-bearing, analgesic and anti-inflammatory medication) and surgical treatment (core decompression) [ 17].
The samples had been obtained by open surgical and core biopsy from 32 premenopausal and 21 postmenopausal Caucasian Australian women, who had had biopsies taken in order to exclude breast cancer and for whom data regarding age, menopausal status, use of HRT, height and weight were available.
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