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Information about age, sex, primary diagnosis, fixation method at the previous surgery, components revised during revision, use of bone graft during revision surgery, date and reason for a second surgical intervention, and date of death were extracted from the SHAR database.
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The ICER was less ($9,100) for the provisional diagnosis to surgery component of the intervention (less health gain and also less cost).
We performed a search using the keywords "ceramic", "alumina", and "total hip replacement/hip prosthesis" in combination with "failure", "fracture", "debris", "diagnosis", "revision surgery", "component breakage", "head", and "risk factors" with no limit regarding the year of publication.
Phaco ECP reduces intraocular pressure (IOP) between baseline (21.54 mm Hg, 95% CI 19.86 to 23.22) and 24 months (14.44 mm Hg, 95% CI 13.63 to 15.25) achieving statistical significance at all time points (p<0.001), but the IOP effect achieved by the cataract surgery component of this dual modality treatment is not addressed.
During revision surgery, retrieved components displayed corrosion of the stem surface as well as increased wear at the head neck junction.
Previous non-union and surgery with components removed were significant risk factors for periprosthetic fracture after revision TKR.
A diagnosis of previous surgery with components removed was associated with twice the risk of periprosthetic fracture compared to loosening, wear, or osteolysis.
In patients with revision TKR, diagnoses of non-union, infection and of previous surgery with components removed were significant predictors of postoperative periprosthetic fracture.
The most frequent underlying diagnosis was loosening, wear, or osteolysis (53%), followed by fracture/dislocation (21%) and failed previous surgery with components removed (20%).
Diagnoses of non-union, infection or previous surgery with components removed were associated with a 4.8-, 2.9- and 2-fold higher risk of fracture, respectively, compared to a diagnosis of loosening, wear, or osteolysis.
In revision TKR cohort, a diagnosis of non-union (HR = 4.9, CI: 1.2 20), infection (HR = 2.9, CI: 1.3 6.4) or previous surgery with components removed (HR = 2.1, CI: 1.3 3.4) increased the risk of postoperative periprosthetic fracture, compared to a diagnosis of loosening/wear/osteolysis. We identified significant risk factors for periprosthetic fracture after primary and revision TKR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com