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Fentanyl 100 μg was administered 10 min before surgery completion, and continuous infusion of propofol, remifentanil, and phenylephrine was discontinued at the completion of surgery.
As such, the maximum blood concentration of aprepitant might not have been reached in some of the patients at surgery completion.
Antiemetic tropisetron 2 mg by intravenous infusion before surgery completion and then 0.1 mg/hour intravenously until postoperative pain management finished.
To minimize bias, all patients with disease recurrence within 2 months after surgery, completion of adjuvant chemotherapy, and a minimum follow-up period shorter than 6 months were excluded from analysis.
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Following agreement from the treating surgeon and GP, eligible patients were invited to participate in the study at their final postsurgical follow-up visit (4 6 weeks after surgery or completion of postsurgical chemotherapy).
In order to minimize non-tumoral uptake of FDG, it is advisable to allow at least 6 weeks post-surgery or completion of radiotherapy prior to performing staging 18F-FDG PET-CT [24].
Substantive deviations from prescribed treatment and rehabilitation Patient destination after hospital discharge One and two year follow-up forms from centres Forms to notify mortality or subsequent surgery for completion and return at any time will be made available for the completion by centre staff.
After surgery, however, completion rate decreased significantly with age.
All other patients underwent surgery after completion of induction.
Pathological response was assessed at definitive surgery on completion of NAC.
Therefore, all four patients underwent emergency surgery before completion of the chemotherapy protocol.
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