Sentence examples for surface transporter from inspiring English sources

This dominantly segregating SLC5A7 mutation truncates the encoded product just beyond the final transmembrane domain, eliminating cytosolic-C-terminus sequences known to regulate surface transporter trafficking.

Several cell surface transporter proteins have been identified as central components in this phenomenon (Gottesman et al, 2002).

Dopamine transporter mutants also showed diminished dopamine binding affinity, reduced cell surface transporter, loss of post-translational dopamine transporter glycosylation and failure of amphetamine-mediated dopamine efflux.

It is a single copy gene encoding the prostaglandin transporter, a 12-transmembrane organic anion cell surface transporter that is expressed in the small intestine.

Therefore, we tested for expression of the cell surface transporter protein associated with differentiation 1 (PAD1), which is a molecular marker for stumpy cells and is not expressed in the dividing slender stage (Dean et al., 2009).

Also surface transporters related to drug resistance and genes related to developmental progression are detected.

Attention has focused on upregulation of cell surface transporters of the ABC family, in particular ABCG2.

It is able to mediate selective toxicity on trypanosomes over mammalian cells by virtue of being concentrated to millimolar levels inside trypanosomes by P2 and other surface transporters.

Diamidines (10, 11) appeared promising since they are rapidly internalized by Trypanosoma brucei via specific surface transporters, including the aminopurine P2/ transporterporter (12 – 14), and several of them are fluorescent (11, 15, 16).

The exploitation of surface transporters peculiar to trypanosomes is a straightforward way to specifically target fluorophores to these parasites, and improved compounds may be developed following this approach to target both human and animal infective trypanosomes.

Since α-cells, but not β-cells possess high level of surface transporters for pyruvate (monocarboxylase transporters) (Ishihara et al, 2003), a potential application of hyperpolarized imaging of pyruvate is to study the physiological and pathological changes specifically in pancreatic α-cells.