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Thus, these cell surface proteins represent novel targets for the development of therapeutics against HIV-1 infection and AIDS.
The cell envelope and surface proteins represent the most obvious candidates for host interaction.
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Thus, FZD proteins represent surface marker molecules that may have a functional role in maintaining progenitor cells.
TvBspA-like proteins represent strong candidate surface proteins mediating interaction with various mucosal landmarks including the mucus; VEC, urethra epithelial cell and other host cells; ECM proteins and vaginal microflora or cell-cell adhesion during parasite swarming.
These proteins represent a large class of cell-surface molecules that act as stimulus receptors, including receptors for neurotransmitters, hormones, growth factors, odor molecules, and light [ 62].
In the shape complementarity evaluation, the surface contact between proteins represented by the grid points is evaluated by using the score function of the contact surface area.
In addition, because claudins are surface proteins, they may represent useful target for various therapeutic strategies.
In order to determine binding characteristics of polyclonal serum antibodies using surface plasmon resonanace (SPR), recombinant HA proteins, representing both H5N1 clades, were characterized (Fig. 7).
Indeed, interactions among extracellular and cell surface proteins are poorly represented in existing protein-protein interaction databases [33] and new methods are needed to enable their discovery.
Genes encoding cell surface proteins were disproportionately represented among the genes that distinguished among the lymphocyte subpopulations.
The unbound (unbiotinylated) proteins, representing the intracellular fraction, were separated from the captured surface proteins by centrifugation of the column.
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