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Most pathogens initiate their infections at the mucosal surface of the respiratory, gastrointestinal and urogenital systems (Marasini et al., 2014).
The primary habitats of human and animal mycoplasmas are the mucous surface of the respiratory and urogenital tracts, the eyes, mammary glands and joints [ 5].
Although the relationship between carriage and disease is not well understood, evidence suggests that local or systemic invasive infection is caused by serotypes that bind to the epithelial surface of the respiratory tract [ 9- 11].
Upon inhalation, O3 is thought to oxidate or peroxidate biological molecules (directly or indirectly) at the surface of the respiratory tract, triggering a pathological cascade characterized by lipid peroxidation, enzyme inactivation, free radical formation, altered membrane permeability, and inflammation (Mustafa 1990).
Final results are shown as 40-Ct using the normalised value, or as fold-change from uninfected controls.> Taqman real-time quantitative RT-PCR analysis was used to measure viral load in trachea samples from both control and infected birds from both lines 15I and N. Tracheal tissue was chosen for examination in this study as the target of IBV is the epithelial surface of the respiratory tract.
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IAV infects the host by gaining access through the nose, mouth or mucosal surfaces of the respiratory tract.
Together, these results indicate virus can be detected at multiple mucosal surfaces of the respiratory system.
Many microbial pathogens invade their human and animal hosts through the mucosal surfaces of the respiratory, gastrointestinal and urogenital tracts [1], [2].
NRL-induced OA, an IgE-mediated process, is initiated when the allergen-bearing particles deposit onto the mucosal surfaces of the respiratory tract.
At the time of euthanasia, the agent could no longer be isolated, unlike previous studies [ 5, 7, 8] and was associated with mild immunoreactivity on the mucosal surfaces of the respiratory, gastrointestinal and urinary tracts.
Mucins are high molecular weight glycoprotein components of mucus (> 250 kDa), which protect and lubricate the epithelial surfaces of the respiratory, gastrointestinal and reproductive tracts in the body [ 1].
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