Sentence examples for sur level from inspiring English sources

Significantly more patients receiving febuxostat than placebo achieved an sUr level of ≤ 0.36 mmol/L) at each visit (P < 0.001 for each comparison).

Durable maintenance of goal range sUr level with either dose of febuxostat or in smaller numbers of subjects with allopurinol resulted in near elimination of gout flares and improved tophus status over time.

The target sUr level (≤0.36 mmol/L) was achieved at study end in 0% of patients in the placebo group and 56%, 76% and 94% of patients in the 40 mg, 80 mg, and 120 mg febuxostat groups, respectively.

Flares requiring treatment, tophus size, safety, and sUr levels were monitored during up to 40 months of ULT maintenance.

In the present study, there was no difference in mean sUr levels between patients with early or late RRT (Table 2).

In patients with high sUr levels who suffer from frequent attacks of gout, the use of urate-lowering drugs is warranted.

This includes sufficient prophylaxis of gout flares during start of antihyperuricemic treatment, choice of drug tailored to patient characteristics, and dosage titration to target sUr levels.

The combined absence of uricase and almost total reabsorption of filtered urate explains that humans (and the greater apes) have 10-fold higher sUr levels than other mammals.

Febuxostat 10 to 120 mg/day dose-dependently reduced mean sUr levels from baseline by 25%to70%0% in healthy volunteers; 24-hour urinary uric acid excretion at day 8 was decreased by 46%to66%6% relative to placebo.

32 However, a strict low-purine diet can achieve only a limited reduction in sUr levels (≤0.10 mmol/L or 1.7 mg/dL), and many patients have difficulty with adhering to long-term dietary changes.

72 Significantly higher percentages of subjects treated with febuxostat 80 mg (48%), 120 mg (65%), and 240 mg (69%) attained the primary endpoint of at least 3 monthly sUr levels <0.36 mmol/L compared with allopurinol (22%) and placebo (0%).