Sentence examples for suppressor effects in from inspiring English sources

The functions of Tregs were determined by assessing the immune suppressor effects in the intestine.

Furthermore, p53 exerts its tumour suppressor effects, in part, through the control of bladder tumour angiogenesis (Grossfeld et al, 1997).

This pathway analysis may explain the observed oncogenic effects of miR-145 in metastatic CRC compared to its reported tumor suppressor effects in the non-metastatic context.

This prompted us to investigate whether reconstitution of miR-204 expression can promote tumor suppressor effects in vitro and in vivo.

It has been shown that TGF- β exerts tumour suppressor effects in normal epithelial cells and in early stage of tumour progression by inducing cell-cycle arrest, senescence and apoptosis.

Hence, we studied the SGK1/FOXO3A-associated effects of p53 versus ANXA7 that were anticipated to reveal the alterations in canonical p53 cell survival control as well as beneficial ANXA7 tumor suppressor effects in the PTEN-deficient LNCaP.

This is consistent with a tumor suppressor effect in well-differentiated tumors [ 3, 4].

Further studies are needed to delineate the mechanisms underlying its tumour suppressor effect in NPC.

We further revealed the molecular basis of how SSTR1 exerts the tumour suppressor effect in gastric cancer.

Over-expression of miR-143 and miR-145 has previously been shown to result in a tumor suppressor effect in non-metastatic CRC cell lines [ 21, 27, 32].

Indeed previous reports have shown that miR-145 leads to a tumor suppressor effect in non-metastatic CRC cell lines (DLD1, HCT116, SW480, LS174T) [ 21, 27].