Sentence examples for suppressor effect from inspiring English sources

It also led to suppressor effect on SPATA 7 gene which is responsible for fertility in males.

The tumor suppressor effect of the NLRC4-inflammasome seems to be primarily from NLRC4 expression in epithelial cells (Hu et al., 2011).

Indeed, restoring Cx43 to glioma cells reduces their rate of proliferation and their tumorigenicity but this tumor suppressor effect could be counterbalanced by its effects on invasiveness, adhesion and migration.

This apparent global suppressor effect suggests that increasing the thermodynamic stability of p16 can be used as a general strategy to restore the biological activity to defective mutants of this important tumor suppressor protein.

This dominant suppressor effect is observed in approximately 50% of the off-spring (N = 75), the rest showing only slight or no suppression.

Thus it is possible that the K5I suppressor effect of the PMAIP1 siRNA reagents are due to an off-target knockdown of Mad2 by the PMAIP1 siRNAs.

Our results showing that ATIP3 re-expression functionally reduces breast cancer cell growth in vitro and in vivo may argue in favor of a tumor suppressor effect of ATIP3.

We first used the 3H-thymidine incorporation assay to test whether hESC-derived NPs exert a direct suppressor effect on the in-vitro proliferation of LNCs obtained from naïve C57BL mice.

The results obtained demonstrated that TRβ1 expression retards tumor growth, causes partial mesenchymal to epithelial cell transition and has a strong suppressor effect on invasiveness, extravasation and metastasis formation in nude mice [22].

All non-contributing variables were excluded one by one with no effect on the suppressor effect.

This is consistent with a tumor suppressor effect in well-differentiated tumors [ 3, 4].