Sentence examples for suppressive systems from inspiring English sources

The motor decision is modeled as a single variable (hereafter, referred to as the execution process) that is assumed to reflect the differential activity between the direct (facilitation) and indirect (suppression) pathways; that is, as facilitatory systems are recruited more than the suppressive systems, the execution process accumulates toward the decision boundary.

These results suggest that CAFs have little direct supportive effect on tumor growth, but play a critical role in immune modulation in TME and that inhibition of CAF function in vivo enhances the potency of DC-based vaccines by dampening the immune suppressive system.

"To launch an election commission at any time on voter fraud would be throwing away resources in a search for mythical creatures ― problems that don't exist ― while failing to address the real problems in our elections systems: suppressive tactics," Hobert Flynn said.

In this present paper, we will summarize the roles of CD73 in cancer development, including its clinical significance in cancer patients, its promotive effects on tumor growth, metastasis, and angiogenesis, and its suppressive effects on immune system under tumor microenvironment, regulation mechanisms of CD73 expression, and opportunities for anti-CD73 cancer therapy in the future.

Importantly, CD8+ T cells in the transwell coculture system had a potent suppressive activity that strongly suppressed the proliferation of the naïve CD4+ T cells.

Demyelination of MOC bundle fibers, weaker inhibitory effect of acetylcholine in the MOC system, and resultant disorders of neurotransmission would constitute potential factors involved in the evolution of the suppressive effect of the MOC system into the stimulation of OHC. 31 In turn, Nieschalk et al 40 analyzed the role of the cochlear enhancer in the presence of low-level CAS.

Although the ALDH1 inhibition-mediated NRF2 suppression seems to be the primary mode of action of ATRA in our system, this additional suppressive action on NRF2 could be beneficial to control CSC resistance.

Transfused blood also has a suppressive effect on the immune system, which increases the risk of infections, including pneumonia and sepsis, he says.

They play a suppressive role in the immune system by the secretion of negative regulatory cytokines such as interleukin-10 or by immune cell contact inhibition.

Potential problems to human may include suppressive effects on the immune system [6, 7], splenic and lymph node damages and carcinogenesis [8, 9].

This supports the hypothesis that the emergence of mutated strains late in infection is related to the limitation in the suppressive capacity of the immune system.