Sentence examples for suppressive pressure from inspiring English sources

Thirdly, the activation of YAP/TAZ could be the result of other growth regulating pathways (i.e. Ras, TGF-β, and Wnt) exerting suppressive pressure on Hippo signaling, such that deregulation of those pathways leads indirectly to the activation of YAP/TAZ [42, 89 95].

While virus-specific cytotoxic T lymphocyte (CTL) responses exert strong suppressive pressure on primary HIV replication [1] [7], the contribution of virus-specific antibodies in clearance of primary HIV infection has remained unclear [8].

Previous studies have demonstrated suppressive effects of AF-16 on increased tissue pressure in tumours [ 8].

Furthermore, phospho-Stat3 can be pro-tumorigenic, suggesting that the aged stem cells, the suggested cell of origin in squamous cell carcinoma, might already be more prone to tumor initiation and that unknown tumor suppressive mechanisms could be acting in opposition to this pressure and contribute to aging.

He pointed to a policy called Disconnection, which pressures Church members to sever ties with anyone declared a Suppressive Person, a Church term for an enemy of Scientology or its principles.

We speculate that tumor cells are under selective pressure to downregulate RBM4 expression, as this would allow tumors to evade tumor-suppressive events such as expression of Bcl-xS and ULBP1.

The evidence as a whole suggests that upregulation of NKG2D ligands on early stage tumor cells is part of a host defense mechanism, but that the immune response subsequently applies selective pressure for tumors that have either extinguished expression of NKG2D ligands or have activated immune suppressive mechanisms (Raulet and Guerra, 2009).

The resulting diversity of infectious agents and host immune-suppressive factors exerts strong selection pressures and favors hosts with a large repertoire of defense responses, including effector molecules with direct defense activity, among which AMPs and peptide families such as the defensins are prominent [ 91].

Still others had been expelled or declared Suppressive Persons.

Kif4A-CCL2 promotexpressioniof of suppressive molecules in macrophages.

Effect of suppressive myeloid TILs in response to checkpoint blockade.