Sentence examples for suppressive for from inspiring English sources

While we and others have shown that RBP-J is essential for host defense against certain intracellular bacterial species, expression of RBP-J in tumor-associated macrophages (TAMs) is suppressive for T-cell mediated anti-tumor immune responses (Franklin et al., 2014).

The 5' end of the gene is important for the gene expression regulation and the methylation of the 5' end is usually suppressive for gene expression.

This result suggests that, even in the relatively immunogenic E.G7 model, the tumor microenvironment is still unfavorable or suppressive for optimal activation of adoptively transferred memory T cells.

Therefore, selective inhibition of IL-12 is likely to be suppressive for cellular immune responses.

The net effect of the 5-HT1 receptor agonist on retinogeniculate transmission is suppressive for low-frequency inputs, but rather ineffective or facilitative for high-frequency inputs.

Allelic variation at the Gct6 locus is either permissive or suppressive for spontaneous GC tumor initiation, with tumor suppressor activity contributed by the CAST strain allele (Gct6 CA).

Refers to patients with immune suppression not related to cancer (for example, those receiving immune suppressive medication for solid organ transplantation, or those with a primary immune deficiency).

Furthermore, via surgical CSX we demonstrate a key suppressive role for androgens in the suppression of resistance to Trichuris in male IL-4KO BALB/c mice.

Consequently, the potential therapeutic benefits of modulating the development and functions of DCs for vaccines against pathogens, tumors, and suppressive therapies for autoimmune diseases have attracted more attention in the research and clinical applications.

Clinicians should consider alternative forms of acid suppressive therapy (for example, histamine-2-receptor antagonists) for indications like stress ulcer prophylaxis.

These findings indicate a tumour suppressive role for ISG15 and highlight a molecular rationale for therapeutic use of doxorubicin [ 28].