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Patients used a suppressive dose of levothyroxin.
Because anthrax can cause massive bacteremia [34], in the second stage, LT might progressively increase and eventually reach an MEK/MAPK suppressive dose, thereby leading to a p38 MAPK dependent inhibition (Fig. 6D-F).
The maximum suppressive dose might be observed at the concentration of 80 mg/L (30.6% inhibition).
Inhibited cell growth by maximum suppressive dose of CT or 8-Cl-cAMP was further inhibited by TPA.
Furthermore, we did not find any relation between Se and thyroid function parameters in the group of oncological patients who were taking T4 medication in a suppressive dose.
Elevated serum Tg (patient taking T4 in suppressive dose) was generally associated with tumours which had 131I concentrating function when stimulated by excess TSH.
Similar(51)
This patient was still on suppressive doses of oral antibiotics at the time of death.
All patients received suppressive doses of L-T4.
When high-dose regimens of primaquine (total 5 6 mg/kg) fail, suppressive doses of chloroquine, 300 mg/week for several months to years may be considered.
An important issue for future studies will be to evaluate the widespread, long-term use of thyroxin treatment in TSH suppressive doses for benign thyroid disease [ 49, 50], and the management of women with subclinical hyperthyroidism [ 51- 53].
The clinical findings, the fact that no patients responded to antibiotic therapy, that many of them were ANA positive and all responded to immune suppressive doses of prednisolone, indicate that the fever and other clinical signs in these dogs were immune-mediated.
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