Sentence examples for suppressive control from inspiring English sources
Malicious information, e.g., a dangerous computer virus, might have catastrophic outcomes calling for suppressive control, while marketing advertisements can be exploited for maximizing online revenues and may be enhanced by an amplifying type of control.
CD4+CD25+FOXP3+ Treg cells are involved in the maintenance of suppressive control of aberrant immune responses.
It is widely accepted that HPV-mediated cervical carcinogenesis proceeds via the integration of viral genome and disruption of the E2 ORF, thus releasing the suppressive control of E2 on the expression of viral oncogenes E6 and E7.
In the case of miR-125b downregulation, this causes a loss of tumor suppressive control mechanisms leading to aberrant activation of multiple oncogenes in a tissue specific manner (see above).
The suppressive control of T lymphocyte responses is a complex event in which the major inductors are Treg cells modulated by numerous factors coming from the immune system or not.
Furthermore, both MC-TG and free TG depleted already differentiated Mo-MDSCs by day 7 in vitro (Fig. 1c), from 3.9 ± 0.7 to 0.2 and 0.3 %, respectively, and rendered BM-derived MDSCs less suppressive than control MDSCs (Fig. 1d).
SNP rs2069522 is located -2847 bp relative to CYP1A2, within a putative region of bi-directional suppressive transcriptional control (position -1329 to -4412) for both CYP1A1 and CYP1A2 genes [ 15], hence it is possible that this sequence change may influence transcription of CYP1A1 and CYP1A2 proteins.
In turn, the miRNAs manifest growth suppressive effects and control cell proliferation in response to E2.
Tregs have suppressive mechanisms and control the threshold for peripheral antigen recognition via tonic down-regulation of dendritic cell (DC) co-stimulation.
Based on the expression of cell surface molecules, including cytotoxic T-lymphocyte-associated antigen (CTLA -4 and forkhead/winged helix transCTLA -4n fandor p3 (forkhead/wingedD25+ Tregs, and cytokines including interleukin (IL)-10 as well as transforming growthelixtranscriptionere analyzed to investigate the factoronal role of TIp32 in controlling suppressive aCD4+CD25+f CD4+CD25+ Tregs.
We observed an immune-suppressive effect in control patients regarding NK cell mediated cytotoxicity, which was overcome in MALP-2-treated patients.
